Win32-fixes-mse.com pop-up disables your browser?

Some users have found that a page of win32-fixes-mse.com domain comes frequently. And then on the screen, they can get a blank except for a pop-up message: “Microsoft Detected Security Error Due to Suspicious Activity. Please Contact Microsoft Certify Live Technicians for Help: 1-717-428-7126.” Some victims close the browser, but if they open new tab, the same pop-ups from win32-fixes-mse.com happen again. Some other users are scared by this pop-up, and do as it says to call the given number.